How can Elicera’s iTANK technology boost CAR-T cell therapies?

Project specs

Category

Biology

Contact

Di Yu

Country

Sweden

Funding agency

Elicera Therapeutics AB & Swedish Cancer Society & Swedish Research Council & Swedish Childhood Cancer Fund & Sjöberg Foundation & Göran Gustafsson Foundation

Length

02:00

Summary

Leveraging CAR-T therapies to fight solid tumors poses challenges since they have a highly immunosuppressive tumor microenvironment and a heterogenous target antigen expression. Elicera aims to resolve these challenges by arming CAR T-cells with its proprietary iTANK technology platform to directly counteract the immunosuppressive tumor microenvironment and elicit a second immune response by activating the patients’ own killer T-cells against the whole set of relevant target antigens on solid tumors.

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