What can supercomputers teach us about viruses?
Summary
Concealed within the walls of a virus particle, the structure of its molecular program – the viral genome – evades precise determination using experimental probes. Computer simulations of genome packaging carried out in steps of increasing resolution enables virtual reconstruction of a complete virion particle, revealing the structure of its genome. Aided by the processing power of a supercomputer, computational microscopy of viruses holds promise of discovering new approaches to fighting viral infections.
