Is the LEI interface the new frontier of LC-MS?
LEI is an LC-MS interface (2016), in which solute and mobile phase vaporization occurs at atmospheric pressure before entering an electron ionization (EI) ion source. EI is unparalleled for the identification of gas-phase molecules. With LEI the same advantages are accessible to LC amenable small molecules for challenging LC-MS applications. LEI inventor, Achille Cappiello is a full professor of Analytical Chemistry at the University of Urbino in Italy.