Nucleic acid nanoparticles as a new molecular tool for communication with the human immune system

Project specs




Kirill Afonin



Funding agency

Research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Numbers R01GM120487 andR35GM139587. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.The study was also funded in part by federal funds from the National Cancer Institute, National Institutes of Health, under contract 75N91019D00024. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government.




Afonin lab at UNC Charlotte and collaborators have worked hard to develop a NANP-based platform that will enable controlled communication with the human immune system to promote its activation beneficial for therapies or reduce its undesirable activation for systemically delivered therapeutics.

Researcher Profile

The Afonin Lab is a diverse group of highly motivated researchers who came from all corners of the world. With each member bringing their own expertise to the table, we are able to address various components of nucleic acid nanotechnology including, but not limited to: nanodesign, immunomodulation, delivery, biosensing, therapeutics, and dynamic structures.

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